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Refine Weight Loss & Skin Preservation Programme

Achieve sustainable weight loss with medical support and natural‑looking skin confidence.

Located in Dublin 2, Refine Clinic has been supporting patients since 2012. Led by Dr. Natalia Bratu — a Medical & Aesthetic Doctor with over 25 years of experience in Dermatology, General Practice and Aesthetic Medicine — our clinic takes a patient‑first approach to weight management and overall wellbeing. 

Many people struggle with weight loss due to busy schedules, stress, hormonal changes or long‑standing habits. This can affect both physical and mental health, leading to frustration, low confidence and reduced quality of life. 

Our doctor‑led programme combines prescription medication, personalised nutrition and lifestyle guidance, and ongoing clinical support — helping you achieve safe, sustainable results while maintaining your natural facial appearance.

What Is the Refine Weight Loss & Skin Preservation Programme?

Our programme is a medically supervised approach to weight loss that includes: 

  • A full medical assessment 
  • Tailored nutrition and lifestyle guidance :  Tailored lifestyle recommendations aligned with your daily routines to protect lean muscle tissue. 
  • Prescription weight‑loss medication (where appropriate): Safe prescription of regulated GLP-1 Receptor Agonist class medications (such as semaglutide or liraglutide, to biologically regulate appetite and support metabolic efficiency. 
  • Ongoing monitoring and support : Regular in-person check-ins with Dr. Natalia to track biometrics, manage side effects, and safely adjust dosages. 
  • Complementary treatments to support your skin during weight loss: Specialized regenerative therapies to prevent facial hollowing or skin laxity as your body composition changes. 

As weight reduces, some patients naturally notice changes in facial volume, elasticity or skin texture. Our holistic programme anticipates these changes and offers optional skin‑support treatments to help you maintain a fresh, natural appearance throughout your journey. 

This integrated approach helps patients lose weight safely while preserving confidence and overall wellbeing. 

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Check Your Suitability

BMI Calculator

Use our BMI Calculator to understand your starting point before beginning the programme. 

Weight Loss Questionnaire 

Check if you’re suitable for our Weight Loss Programme by completing our short, helpful questionnaire.

Benefits of the Programme 

Supports Sustainable
Weight Loss  

Lose weight steadily and safely
under medical supervision.

Reduces Appetite and Improves Metabolic Function 

Prescription medication helps regulate appetite and support healthier eating patterns.

Improves Overall Health 

Weight loss may improve conditions such as prediabetes, diabetes, hypertension, high cholesterol and sleep apnoea.

Doctor-led Support Throughout 

You’ll have ongoing guidance from Dr. Natalia Bratu and our clinical team.

Boosts Confidence and Wellbeing 

Patients often report improved energy, mood and self-esteem.

What to Expect

1

Initial Consultation

Dr. Natalia Bratu will assess your medical history, lifestyle, weight-loss goals and suitability for treatment. Your consultation and first treatment may take place during the same visit. 

2

Personalised Plan

You’ll receive a tailored programme that may include prescription medication, nutrition guidance, lifestyle recommendations and complimentary treatments to maintain naturally healthy skin.

3

Treatment and Monitoring

If suitable, medication is prescribed and administered with full guidance. You’ll have regular check-ins to monitor progress and adjust your plan as needed.

4

Ongoing Support

We provide continuous support to help you stay on track and maintain your results long term.

Supporting Your Skin During Weight Loss

Weight loss brings incredible health benefits — but it can also lead to natural changes in the skin, especially on the face, neck and jawline. These changes vary from person to person and depend on age, genetics, speed of weight loss and lifestyle. 

Here are the most common changes patients notice: 

Mild to Moderate Facial Hollowing 
As facial fat reduces, the cheeks and temples may appear less full, which can make the face look tired or drawn.  

Loss of Elasticity 
Skin that was previously supported by volume may feel loose, particularly around the jawline and neck.  

Dullness or Dryness 
A calorie deficit and reduced nutrient intake can affect hydration and skin barrier function.  

More Visible Fine Lines 
With less underlying support, fine lines may appear more noticeable.  

Early Signs of Sagging 
Reduced collagen and elastin can contribute to mild laxity in the lower face.  

At Refine Clinic, we take a holistic approach to our treatments and patient care. Alongside your weight-loss programme, we offer optional treatments that help maintain a fresh, natural appearance throughout your journey. The treatment chosen depends on individual circumstances and is agreed upon with Dr. Natalia Bratu.  

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Complementary Skin Support Treatments

These treatments are entirely optional and tailored to your needs. Many patients choose them to maintain a youthful, natural look as they lose weight. 

Exosomes

Exosomes Treatment Dublin

Boost collagen, improve texture and restore radiance.

PRP (PlateletRich Plasma) 

plasma pen

Supports skin regeneration and improves firmness.

NCTF®135HA Mesotherapy

thread face lift

Replenishes hydration, vitamins and amino acids.

Polynucleotides

polynucleotides

Improve elasticity and support undereye, face and neck rejuvenation.

Hydroboosters

(Ejal 40, Profhilo)

Restore hydration and prevent crepiness.

Dermal Fillers

Portfolio - Stylage Dermal Fillers

Replace structural support in cheeks, temples, chin and jawline.

Threads

relife-threads-featured

Lift and support areas affected by early sagging.

Lanluma (Biostimulator)

Stimulates collagen for long-lasting firmness.

Skinade (Drinkable Collagen Supplement)

Skinade Collagen Drinks Woman 2

Supports collagen production from within, improving hydration, elasticity and overall skin quality during weight loss.

Skinvive by Allergan (Microdroplet Hyaluronic Acid)

hydrobooster - SkinVive

Improves skin smoothness, hydration and luminosity, making it ideal for restoring glow as facial volume reduces.

Results

Results vary depending on medication type, dosage, lifestyle and commitment to the programme. Dr. Natalia Bratu will guide you through realistic expectations and timelines. Many patients experience:

1 dress size dropped in less than 1 month.

1 stone (6.35 kg) lost in the first month.

3 stone (19.05 kg) lost over 6 months.

Refine Your Health, Confidence and Wellbeing 

Start your medical weight loss journey today. 

Why Choose Refine Clinic

Doctor-led Aesthetic & Medical Care

Led by Dr. Natalia Bratu, we provide
personalised consultations and tailored treatments while ensuring the highest standards of safety and effectiveness for each procedure.

Natural, Subtle, Confident Results

All our treatments at Refine Clinic aim to achieve results that retain your natural beauty and boost your confidence.

Patient-first Approach

At Refine Clinic, we understand that every patient has unique needs and wishes. That’s why we take the time to get to know our clients, making each visit and procedure a rewarding experience.

Precision, Expertise and Safety

Dr. Natalia Bratu has over 25 years of experience in dermatology, general practice and aesthetic medicine, with safety a constant consideration throughout the treatment process.

Pricing

Weight Loss Programme Price
Consultation €100
Video Consultation €100
Follow Up Consultation €75

Pre & Post Treatment Advice

To ensure your treatment runs smoothly, we recommend the following: 

  • Avoid non‑steroidal anti‑inflammatory drugs (NSAIDs) such as ibuprofen, Ponstan or Difene for 2–3 days before treatment. 
  • Inform us of any medical conditions, medications or recent changes to your health. 
  • Ensure you are well‑hydrated in the days leading up to your appointment. 
  • If you bruise easily, consider taking a high‑strength arnica supplement for a few days before treatment. 
  • If you have any concerns before your appointment, please contact the clinic — we're here to help. 

To support your recovery and results: 

  • Follow your doctor’s instructions regarding medication use and dosage. 
  • Stay well‑hydrated and maintain a balanced diet. 
  • Avoid alcohol for 24 hours after injections. 
  • Avoid strenuous exercise for 24 hours, as this may increase bruising. 
  • If you experience mild redness or tenderness at the injection site, this is normal and should settle quickly. 
  • Contact us if you have any concerns — our team is always available to support you. 

Frequently Asked Questions

Your programme is overseen by Dr. Natalia Bratu, who will guide you through every step of your treatment. She will discuss your medical history, suitability, benefits, risks and expected results during your consultation.

Suitability depends on your medical history, lifestyle and current health. Some patients may not be suitable due to pre‑existing conditions or medications. Dr. Bratu will assess this during your consultation and advise you on the safest options. 

GLP-1 (glucagon-like peptide-1) receptor agonists are licensed prescription-only medications, such as semaglutide  or liraglutide). They work by mimicking a natural hormone released by the gut after eating. This acts on the brain to reduce appetite, delay stomach emptying, and create a lasting feeling of satiety. 

No. Refine Clinic strictly rejects the unguided “prescription-only mill” model. Rapid weight loss without lifestyle changes leads to severe muscle wasting (sarcopenia) and an immediate weight rebound once the medication is stopped. We only prescribe GLP-1 therapies as supportive tools alongside active nutritional coaching and resistance training to preserve lean muscle and protect your metabolic rate.

Most patients find the injections very manageable. A nurse specialist will guide you through the technique and ensure you feel comfortable and confident. 

The most common side effects are gastrointestinal, including mild nausea, indigestion, constipation, or transient fatigue. These symptoms are usually mild and temporary. Dr. Natalia starts your treatment at a low dose and increases it slowly to minimize discomfort, monitoring you closely at every step. 

Many patients notice changes within the first few weeks. Results vary depending on dosage, lifestyle and commitment to the programme. 

Yes. Many patients choose complementary treatments such as exosomes, PRP, NCTF®135HA, polynucleotides, hydroboosters, fillers or threads to maintain a youthful, natural appearance during weight loss. 

Never. At Refine Clinic, we take a patient‑first approach. You are free to take your time, consider your options and return when you feel ready. 

You will have regular check‑ins with the clinic to ensure your progress is safe, steady and aligned with your goals. 

Results are long‑lasting when combined with healthy lifestyle habits. Your doctor will guide you on how to maintain your progress after completing the programme. 

You are always welcome to contact the clinic. Our team is here to support you throughout your journey. 

What Our Clients Say

 
 
 
 
 
 
 
  
 
 
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 Joanna Kaniecka profile picture 
 
 
 Joanna Kaniecka 
 
 
 
 Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google. 
I am delighted with my skin check. Dr. Natalia was very nice and friendly. The mole exam was quick and comfortable. Calm and relaxing atmosphere. I highly recommend Refine Clinic 🥰
  
 
  
 
 
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 Mark Roche profile picture 
 
 
 Mark Roche 
 
 
 
 Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google. 
Natalia is a really good dermatologist..I have had several appointments with her over the last 4 months and all have been really positive ..she listens to her patients then she puts a plan in place .im really happy with the results ive gotten.. my dry skin and eczema have improved so much ..the clinic is really nice and bright and your always seen on time ..the reception staff are really nice and they couldn't  be more helpful..I would recommend people who have skin conditions long term or even short term  to give natalia a try they won't be disappointed
  
 
  
 
 
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 Ana Luíza Klingl profile picture 
 
 
 Ana Luíza Klingl 
 
 
 
 Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google. 
Dr. Natalia has been truly exceptional. She not only helped me improve my skin, but also regain my self-esteem throughout the process. I’m genuinely grateful for her care, expertise, and dedication.
  
 
  
 
 
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 Ali Ismail profile picture 
 
 
 Ali Ismail 
 
 
 
 Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google. 
I had a great experience at Refine Clinic in Dublin. From the moment I arrived, the staff were incredibly helpful and made me feel genuinely welcome, which immediately put me at ease. Dr Natalia is outstanding—she really takes the time to listen carefully and understand your concerns. Her expertise and thoughtful approach make you feel confident that you’re in the best hands. She explains everything clearly and tailors her recommendations to suit you as an individual. Overall, a professional, friendly, and reassuring experience. I would highly recommend Refine Clinic to anyone considering treatment.
  
 
  
 
 
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 Lilian Tabuncic profile picture 
 
 
 Lilian Tabuncic 
 
 
 
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Good
  
 
  
 
 
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 Sara Abratanska profile picture 
 
 
 Sara Abratanska 
 
 
 
 Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google. 
I have been going to Dr Natalia for some time now and I could not be happier with results! She is so kind and professional, always tailors treatments to the patient! I had a stubborn lesion removed and it has healed perfectly, she is a pro!
  
 
  
 
 
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 M You profile picture 
 
 
 M You 
 
 
 
 Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google. 
Dr Natalia is the best - she helped me solve skin issues I have been battling with for a long time. Definitely recommend!
  
 
  
 
 
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 Aoife March profile picture 
 
 
 Aoife March 
 
 
 
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Natalia is the most helpful and professional consultant. Everyone greets you with a smile and the friendliest nature. Can't recommend Refine cinic enough. They've recently moved offices and the new office is beautiful. An amazing experience always!
  
 
  
 
 
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 Elena Bratu profile picture 
 
 
 Elena Bratu 
 
 
 
 Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google. 
I had my first dermatology consultation for my face at Refine Clinic and I am very pleased with the experience. Starting with the lovely girls at the reception, who were wonderful and welcoming, all the way to the doctor, who explained everything very clearly, I felt very well taken care of. I also received the appropriate treatment for my condition. I highly recommend this clinic.
  
 
  
 
 
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 krasniy1000 profile picture 
 
 
 krasniy1000 
 
 
 
 Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google. 
A truly amazing dermatologist. She explained everything and gave recommendations. I recommend her to everyone. Действительно отличный доктор. Профессионал своего дела. Спасибо, была рада знакомству . Желаю вашей клинике процветания.

Medical Disclaimer

The information on this page is intended for informational purposes only and does not constitute medical advice. All treatments at Refine Clinic are performed by or under the supervision of Dr. Natalia Bratu IMC 335160, a fully registered medical practitioner. Individual results may vary. A consultation is required before any treatment to assess suitability