What are Exosomes?

Exosomes have started grabbing attention in the field of skincare and dermatology due to their potential role in promoting skin health and rejuvenation.

Research has suggested that when exosomes are derived from stem cells or other cell types they can influence various cellular processes in the skin, including cell proliferation, differentiation, and tissue repair.


What are they used for?

Anti-aging effects: Exosomes may contain growth factors, cytokines, and other signaling molecules that promote collagen production, improve skin elasticity, and reduce the appearance of wrinkles. By delivering these bioactive molecules to skin cells, exosomes could potentially help in combating signs of aging.

Wound healing: They have been shown to accelerate wound healing by promoting cell migration, proliferation, and angiogenesis (the formation of new blood vessels). This property makes them promising for treating skin wounds, cuts, and burns.

Skin rejuvenation: When exosomes are derived from stem cells or young cells, they may have rejuvenating effects on aging skin by stimulating the production of new skin cells, improving skin texture, and enhancing overall skin appearance.

Skin hydration and barrier function: Exosomes can improve skin hydration and strengthen the skin barrier by delivering lipids and other molecules essential for maintaining skin moisture and integrity.

Treatment of skin disorders:  There is some research to show that exosomes are potentially effective in treating various skin disorders., such as eczema, psoriasis, and acne. By modulating inflammation, immune response, and other cellular processes, exosomes could offer novel therapeutic strategies for these conditions.

Purasomes by Dermaroma

Purasomes are unique multi-patented anti ageing, skin glowing  and hair restoring formulations with organic colostrum derived exosomes, growth factors and biologically active elements working synergistically by elevating human body’s natural healing response and resetting cellular performance to the level of younger age.


Purasomes NC150+ Nutri-Complex

A powerful regenerative mechanism, activated by unique Purasomes  NC150+ formula, amplifies collagen production, triggering formation of  fibroblasts in the dermis,  essential for new cell growth; dramatically  improves  skin structure, its strength, and elasticity.

Angiogenesis is the creation of new blood vessels. It is stimulated by 20 functional Growth Factors derived from the richest source of growth factors and exosomes existing in nature,  play a vital role in skin health and functionality.

The ability of Purasomes to promote angiogenesis significantly contributes to skin remodeling. This allows the creation of new cells with new blood supply. It also accelerates the recovery process of sustained tissue damage caused by chrono ageing.

Purasomes Nutri Complex is a perfect treatment for those who are experiencing age related skin changes, seeking for non surgical options and choose natural approach.



Works on mature, dry, distressed and chronologically or photo damaged skin by drastically amplifying cellular performance.


Repairs deepest layers of skin.Supports collagen formation and maintains skin firmness and elasticity.


Deeply nourishing and replenishing. Enhanced penetration ability.

Promotes angiogenesis and new tissue formation.


Determines new skin quality.

Creates long term resilient skin framework, defined contour and firmer skin.

Purasomes SGC100+ Skin Glow Complex

PURASOMES SGC100+ Complex revitalizes skin for vitality and rebuilds a flawless and luminous skin complexion.

Skin Glow Complex contains 20 Billion organic colostrum exosomes and 20 functional factors which promote cells turnover, accelerate blood vessel formation, facilitate skin healing and decrease inflammation, a major contributor to skin aging.

Lumina granatum seed stem cells, a unique skin friendly brightening agent, and concentrated stable vitamin C derivative improve overall skin tone, decrease age spots and pigmentation, revealing even and glowing skin.

Putasomes SGC 100+ contains unique skin friendly synergistic combinations, brightening agents and major anti oxidants resulting in rebuilding flawless skin complexion.

50 mg of low molecular weight Hyaluronic Acid and 50mg of high molecular weight Hyaluronic Acid keeping the skin hydrated and moisturized.

Growth factors and peptides have a strong anti oxidant effect and create a resilient long lasting protective skin barrier.



Melanosynthesis & melanotransportation. Significant decrease of pigment formation. Melanophillin production reduction.


Revitalising skin for radiance and vitality. Enhancing skin brightening and luminosity. Preventing free radicals.


Creates long lasting protective barrier and strong antioxidant effect against sun radiation.

Purasomes HSC50+ Hair & Scalp Complex

Purasomes HSC50+ is a powerful hair rescue formula designed to restore normal hair growth synchrony by resetting hair bulbs and reactivating their normal functionality. This is due to the unique ability of exosomes and growth factors to reprogram skin cells.

Signaling molecules carried out by exosomes improve scalp health, fight inflammation and reactivate dormant hair follicles.

20 Billion exosomes, 20 functional growth factors, curcuma longa stem cells and a unique peptide complex work together preventing hair from apoptosis driven regression. This creates the optimal environment for healthier, stronger and thicker  hair regrowth.

25 mg of low molecular weight hyaluronic acid and 25mg of high molecular weight hyaluronic acid seal in the moisture and allow the hair and scalp to retain it.



Resets strength of dermal papilla, stops hair loss. Hair restructure & reinforcement.


Remodels hair follicle’s microenvironment.


Restores hair growth synchrony. Regulates hair formation and growth cycles.


Determines the quality of new hair. Healthy, hydrated scalp. Stronger, denser and thicker hair.

Pre & Post Treatment Advice

Prior to treatment the intake of non-steroidal anti-inflammatory drugs (NSAID) must be avoided. 48-72 hours before the treatment. Anti-inflammatory drugs include ibuprofen (Nurofen), mefanamic acid (Ponstan), diclofenac (Difene) and others

We always recommend to patients who would bruise easily or are unsure if they bruise easily to take a high strength freshly prepared arnica supplement for a few days before treatment

  • In general, to reduce bruising in this area it is advised to apply pressure to the injection site for 3-5 minutes afterwards.
  • We always recommend to patients who would bruise easily or are unsure if they bruise easily to take a high-strength freshly prepared arnica supplement for a few days before treatment and to keep taking it for 3-5 days post-treatment. You can buy this high-strength (200c) arnica in health shops and homoeopathy stores.
  • Arnica cream is also very effective to bring down any bruising and swelling post-treatment.
  • As with any facial treatment it is advised to stay out of direct sunlight as much as possible and to avoid using any harsh toners or cleansers on the treated area.
  • It is best to avoid strenuous exercise post-treatment as it may cause bruising.
  • If you have any queries regarding post-treatment, please don’t hesitate to contact us or ask before leaving the clinic.

Frequently Asked Questions

1 treatment – 350 euro
2 treatments – 600 euro prepaid
3 treatments – 900 euro prepaid.

Exosomes are applied topically, so they should be a totally pain-free treatment, without any downtime. Plus, when it used in conjunction with other treatments, such as laser, they can reduce the discomfort felt post-procedure, and maximise results.

We are a doctor-led and patient-centric clinic so Dr Natalia Bratu will be looking after you and will have a full consultation with you to discuss your medical health and suitability, benefits, risks, results and post-treatment expectations.

A small number of people are not suitable for treatment. This can be down to pre-existing medical conditions, Your lifestyle, and current physical condition.

At your consultation, the doctor may deem you unsuitable for treatment. In the Refine Clinic we do not pressure our clients to go ahead with any treatment until they are ready so there is no problem if you decide to come back another day and take time to consider your treatment options.

Exosomes are said to continue being active in the skin up to six to eight months post-treatment, leading to maintained skin quality improvements.

As exosomes work by triggering your skin’s natural repair processes, the results aren’t instant, with the best outcomes 3-6 weeks after their use due to their triggering of increased collagen and elastin production. However, due to their anti-inflammatory effect on the skin, they can quickly reduce the downtime of other tweakments, which can be useful while you wait for their full effect.

That is no problem at all. Your doctor will take their time with you.  They will go through the treatment and will answer all your questions to reassure you. If you decide not to have treatment at any point, that is also no problem.  There may be other different treatments that you may be more comfortable with if appropriate for the issues or needs you have.