What Are Exosomes & How Do They Work?

Exosomes now attract attention in skincare, hair rejuvenation, and dermatology because they actively promote skin health and rejuvenation. In hair loss therapy, exosomes derived from mesenchymal stem cells actively stimulate hair follicles and support the growth (anagen) phase.

Research has suggested that when exosomes are derived from stem cells or other cell types they can influence various cellular processes in the skin, including cell proliferation, differentiation, and tissue repair.

Exosomes - hair

Purasomes HSC50+ Hair & Scalp Complex

Purasomes HSC50+ Hair & Scalp Complex actively stops hair loss and regenerates hair follicles to restore normal function.

It resets the strength of the dermal papilla, stopping hair loss and creating a better environment for hair to grow. This regulates the hair growth cycle, allowing stronger and thicker hair to grow through on a healthy and hydrated scalp.

Exosomes reduce inflammation around hair follicles, a common barrier to regrowth. They also have regenerative properties that can help rejuvenate damaged or dormant follicles, encouraging hair growth in areas that may have stopped producing hair.

exosomes-hsc50

Re.Set

Resets strength of dermal papilla, stops hair loss. Hair restructure & reinforcement.

Re.Model

Remodels hair follicle’s microenvironment.

Re.Store

Restores hair growth synchrony. Regulates hair formation and growth cycles.

Re.Define

Determines the quality of new hair. Healthy, hydrated scalp. Stronger, denser and thicker hair.

Benefits of Exosome Therapy for Hair Loss

Anti-aging effects: Exosomes contain growth factors such as cytokines, and other signaling molecules. These molecules promote collagen production, improve skin elasticity, and reduce the appearance of wrinkles. By delivering these bioactive molecules to skin cells, exosomes could potentially help in combating signs of aging.

Wound healing: Researchers have shown that exosomes accelerate wound healing by promoting cell migration, proliferation, and blood vessel formation. This property makes them promising for treating skin wounds, cuts, and burns.

Skin rejuvenation: When exosomes are derived from stem cells or young cells, they may have rejuvenating effects on aging skin by stimulating the production of new skin cells, improving skin texture, and enhancing overall skin appearance.

Skin hydration and barrier function: Exosomes can improve skin hydration and strengthen the skin barrier by delivering lipids and other molecules essential for maintaining skin moisture and integrity.

Treatment of skin disorders:  Some research indicates that exosomes may effectively treat various skin disorders, including eczema, psoriasis, and acne. By modulating inflammation, immune response, and other cellular processes, exosomes could offer novel therapeutic strategies for these conditions.

Ideal Candidates for Exosome Hair Treatment

Exosome therapy is an excellent option for individuals looking to address thinning hair or early-stage hair loss without undergoing surgery. It is particularly suited to:

  • Anyone with early to moderate hair thinning, especially those experiencing androgenetic alopecia (genetic pattern hair loss).

  • People noticing a reduction in hair density or volume over the crown, hairline, or parting line.

  • Post-partum related issues – increased shedding after pregnancy.

  • Clients seeking to boost results after a hair transplant or to maintain healthy follicles long-term.

  • Individuals with hair loss due to stress, illness, or scalp inflammation, provided underlying conditions have been assessed and managed.

Exosome hair treatment is also an excellent choice for those who:

  • Want a non-surgical, minimally invasive approach to hair restoration.

  • Prefer a treatment with little to no downtime, allowing a quick return to daily activities.

  • Are looking for a natural-looking enhancement rather than a dramatic or artificial change.

During your consultation at Refine Clinic, Dublin, Dr. Natalia Bratu will evaluate your hair and scalp health, discuss your medical history, and determine whether exosome therapy is the right option for you. In some cases, combining exosome therapy with other treatments such as PRP hair restoration or microneedling can deliver even better results.

Why Choose Refine Clinic for Exosome Therapy

At Refine Clinic, we understand that hair loss can be a deeply personal and emotional experience. That’s why we offer a science-backed, doctor-led approach to hair restoration, in a calm, discreet setting in the heart of Dublin.

Dr. Natalia Bratu personally oversees every exosome therapy treatment. She is our experienced medical doctor with a special interest in aesthetic and regenerative medicine. You’re in trusted, medically trained hands from consultation to results.

We use clinically proven, high-purity exosomes sourced from reputable laboratories to ensure the best outcomes. Our treatments are designed to stimulate hair follicles, reduce scalp inflammation, and promote long-term hair regeneration — all without surgery or downtime.

Pre & Post Treatment Advice

Prior to treatment the intake of non-steroidal anti-inflammatory drugs (NSAID) must be avoided. 48-72 hours before the treatment. Anti-inflammatory drugs include ibuprofen (Nurofen), mefanamic acid (Ponstan), diclofenac (Difene) and others

We always recommend to patients who would bruise easily or are unsure if they bruise easily to take a high strength freshly prepared arnica supplement for a few days before treatment

  • In general, to reduce bruising in this area it is advised to apply pressure to the injection site for 3-5 minutes afterwards.
  • We always recommend to patients who would bruise easily or are unsure if they bruise easily to take a high-strength freshly prepared arnica supplement for a few days before treatment and to keep taking it for 3-5 days post-treatment. You can buy this high-strength (200c) arnica in health shops and homoeopathy stores.
  • Arnica cream is also very effective to bring down any bruising and swelling post-treatment.
  • As with any facial treatment it is advised to stay out of direct sunlight as much as possible and to avoid using any harsh toners or cleansers on the treated area.
  • It is best to avoid strenuous exercise post-treatment as it may cause bruising.
  • If you have any queries regarding post-treatment, please don’t hesitate to contact us or ask before leaving the clinic.

Frequently Asked Questions

1 treatment – 350 euro
2 treatments – 600 euro prepaid
3 treatments – 900 euro prepaid.

Exosomes are applied topically, so they should be a totally pain-free treatment, without any downtime. Plus, when it used in conjunction with other treatments, such as laser, they can reduce the discomfort felt post-procedure, and maximise results.

We are a doctor-led and patient-centric clinic so Dr Natalia Bratu will be looking after you and will have a full consultation with you to discuss your medical health and suitability, benefits, risks, results and post-treatment expectations.

A small number of people are not suitable for treatment. This can be down to pre-existing medical conditions, Your lifestyle, and current physical condition.

At your consultation, the doctor may deem you unsuitable for treatment. In the Refine Clinic we do not pressure our clients to go ahead with any treatment until they are ready so there is no problem if you decide to come back another day and take time to consider your treatment options.

In short, Initial improvements in 4–6 weeks; full effect in several months.

As exosomes work by triggering your skin’s natural repair processes, the results aren’t instant, with the best outcomes 4-6 weeks after their use due to their triggering of increased collagen and elastin production.

However, due to their anti-inflammatory effect on the skin, they can quickly reduce the downtime of other tweakments, which can be useful while you wait for their full effect.

Exosomes are said to continue being active in the skin up to six to eight months post-treatment, leading to maintained skin quality improvements.

That is no problem at all. Your doctor will take their time with you.  They will go through the treatment and will answer all your questions to reassure you. If you decide not to have treatment at any point, that is also no problem.  There may be other different treatments that you may be more comfortable with if appropriate for the issues or needs you have.