Definisse Peel Program

Definisse Peel Program

Introducing the Definisse Peel Program

Multi-level skin resurfacing

The Definisse Peel Program achieves a multi-level synergistic effect due to components acting on different skin layers. This complementary synergy between its components means that lower concentrations of active ingredients are used. So, this reduces potential damage to treated skin structures and promotes faster skin repair.


The Types of Definisse Peels

Definisse Oily Skin Pre-Peel Definisse Dry Skin Pre-Peel Definisse Classic Peel Definisse Lightening Peel Definisse Neutralizing Buffer

Definisse oily skin pre-peel: 

  • For combination-oily and acne-prone skin.
  • Cleanses the skin with a degreasing effect and evens out the skin’s pH.

Definisse dry skin pre-peel:

  • For thin, dry, and sensitive skin.
  • It cleanses the skin gently and evens out the skin’s pH.

Definisse classic peel:

  • Photo-ageing
  • Superficial actinic wrinkles
  • Expression lines
  • Post-acne skin imperfections
  • Superficial scars
  • Seborrhoeic skin
  • Stretch marks

Definisse lightening peel:

Definisse lightening peel has the same indications as the classic peel plus the following indications below:

  • Localized hypomelanosis
  • Melasma from pregnancy or contraceptives
  • Melanotic pigmentation
  • Marks caused by photo-ageing

Definisse™ neutralizing buffer:

Effectively but delicately neutralizes acids that remain on the skin after a peel, maintaining the skin’s pH.

The Priming Phase

Priming is essential for at least 2–4 weeks prior to the procedure.

It helps to reduce recovery time, facilitates uniform penetration of the peeling agent, detects intolerance to any agent, enforces patient compliance, and reduces the risk of complications.

During the two weeks prior to the outpatient treatment, it will be necessary to prepare the skin using specific products:

  • These are cosmeceuticals chosen according to the clinical history, based, for example, of alpha-hydroxy acids; the appropriately prepared skin will achieve better re-epithelisation once the treatment is complete.
  • Daily use of topical tretinoin strictly under medical prescription could facilitate the smooth penetration of the peeling agent, as well as the daily application of sunscreen could prevent post-inflammatory hyperpigmentation.
  • In patients with history of herpes simplex, antiviral therapy with acyclovir or famciclovir is recommended, beginning two days prior to the procedure and continued for 7-10 days until complete re-epithelialisation.
  • If necessary, a patch test can be performed to keep out the risk of allergic reactions or other adverse reactions. The test is performed near the treatment area, for example behind the ear, preparing the skin for the peeling. The tested area is reevaluated 3 days after for the presence of skin reactions.

Instructions for the patient before treatments.

  • Avoid tanning and direct sun exposure in the two weeks before the treatment.
  • During the treatment apply a sunscreen SPF 30 or higher.
  • Apply the topical products prescribed to prepare the skin for the treatment.
  • Follow the medical doctor’s instructions for the application of products containing high-intensity alpha-hydroxy acids and retinoids.
  • Before starting the treatment, consult your own MD for the presence of changing or bleeding lesions.
  • The treatment area must be free from open pimples, lesions, or skin infections.

The Procedure & What to Expect


The pre-peel chosen is dependent on your skin type. It is then applied evenly on the areas to be treated using cotton wool or gauze. Any remaining excess is removed, and it’s not necessary for this to be rinsed off.

Chemical Peel

The Definisse peel is applied to your skin using a fan brush. After two minutes a whitish coating will appear which is due to the solvent evaporating. Depending on the desired effect, Dr. Natalia may repeat the application of the chemical peel.

Neutralizing Buffer

The neutralizing buffer is applied to the skin using a fan brush. The buffer is left to work for a few minutes, then removed with cotton wool or gauze. A soothing cream is then applied, and there is no need to rinse it off. There is a possibility you may experience a brief burning sensation and redness may occur immediately after the Definisse peel.


Before & After Treatment Results


Side Effects & Things to Remember

Like all peel treatments, this exfoliative product is not recommended if you have:

  • Herpes simplex in the area to be treated.
  • History of development of post inflammatory hypertrophic scars and hyperpigmentation.
  • Undergone recent surgery, laser treatment or dermabrasion in the area to be treated.
  • Undergone previous radiotherapy in the area to be treated which could compromise the regeneration of skin cells.
  • Are pregnant, breastfeeding, or have a known hypersensitivity to the ingredients.
  • Are ongoing treatment or have had recent treatment with isotretinoin or retinoids.
  • Refuse to use sun protection following treatment.

Warning: skin phototypes with higher melanin content (from IV and upwards on the Fitzpatrick scale) may be at greater risk of hyperpigmentation of the treated area. It is not recommended to undergo exfoliative treatment during times of year when the sun is strong because solar radiation can cause hyperpigmentation.1

Contact us for more information on Definisse Peel Program.

Appointments can be made via our Booking Page, email, or via phone. Please be advised that our secretary may need to ask some personal questions to help decide which appointment type is most suited to your needs.